Article
Positive and negative selection on noncoding DNA close to protein-coding genes in wild house mice.
Molecular biology and evolution - 1 Mar 2011
Kousathanas Athanasios, Oliver Fiona, Halligan Daniel L, Keightley Peter D
Abstract excerpt
During the past two decades, evidence has accumulated of adaptive evolution within protein-coding genes in a variety of species. However, with the exception of Drosophila and humans, little is known about the extent of adaptive evolution in noncoding DNA. Here, we study regions upstream and downstream of protein-coding genes in the house mouse Mus musculus castaneus, a species that has a much larger effective...
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