Article
Membranoproliferative pattern of glomerular injury associated with complement component 9 deficiency due to Arg95Stop mutation.
Clinical and experimental nephrology - 1 Feb 2011
Miura Takayoshi, Goto Shin, Iguchi Seitaro, Shimada Hisaki, Ueno Mitsuhiro, Nishi Shin-ichi, Narita Ichiei
Abstract excerpt
BACKGROUND: Arg95Stop mutation of exon 4 in complement component 9 (C9) gene is common in individuals in Japan with C9 deficiency (C9D); however, understanding of the influences of C9D on human glomerulonephritis remains elusive. METHODS: A total of 1288 patients with chronic kidney disease (CKD) were recruited from the hospitals in Niigata prefecture. They were screened for the Arg95Stop mutation of C9 gene by...
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