Article
EGFR mutation detection in NSCLC--assessment of diagnostic application and recommendations of the German Panel for Mutation Testing in NSCLC.
Virchows Archiv : an international journal of pathology - 1 Jan 2011
Penzel Roland, Sers Christine, Chen Yuan, Lehmann-Mühlenhoff Ulrich, Merkelbach-Bruse Sabine, Jung Andreas, Kirchner Thomas, Büttner Reinhard, Kreipe Hans H, Petersen Iver, Dietel Manfred, Schirmacher Peter
Abstract excerpt
EGFR mutation testing in non-small cell lung cancer (NSCLC) is a novel and important molecular pathological diagnostic assay that is predictive of response to anti-epidermal growth factor receptor (EGFR) therapy. A comprehensive compilation of a large number of EGFR mutation analyses of the German Panel for Mutation Analyses in NSCLC demonstrates (a) a higher than previously reported mutation frequency outside...
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