Article
Dealing with NSCLC EGFR mutation testing and treatment: A comprehensive review with an Italian real-world perspective.
Critical reviews in oncology/hematology - 1 Apr 2021
Malapelle Umberto, Pilotto Sara, Passiglia Francesco, Pepe Francesco, Pisapia Pasquale, Righi Luisella, Listì Angela, Bironzo Paolo, Belluomini Lorenzo, Tabbò Fabrizio, Reale Maria Lucia, Russo Gianluca, De Luca Caterina, Novello Silvia, Troncone Giancarlo
Abstract excerpt
Since their discovery, relevant efforts have been made to optimize the detection approaches to EGFR mutations as well as the clinical management of EGFR-mutated NSCLC. The recent shift from single gene testing to novel comprehensive detection platforms along with the development of new generation tyrosine kinase inhibitors, targeting both common and uncommon EGFR-mutations, is leading to a progressive increase in...
Topics
- ErbB Receptors
- Humans
- Italy
- Lung Neoplasms
- Mutation
- Protein Kinase Inhibitors
- Quality of Life