Article
[The study on relation of HLA-DRB1 gene polymorphism to Keshan disease and its association and linkage in the core families].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Feb 2007
Wei Jin, Niu Xiao-lin, Dong Xin, Wang Ya-ping, Zhu Jian-hong
Abstract excerpt
OBJECTIVE: To investigate HLA-DRB1 gene polymorphism in patients with Keshan disease (KD) in the north of China, and its relation to KD in the core families. METHODS: Polymerase chain reaction-sequence specific oligonucleotide probe (PCR-SSOP) method was used to determine HLA-DRB1 genotypes in 118 KD patients, including 63 with latent KD and 55 with chronic KD. Sixty-five normal from the same area were selected...
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