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Article

Protein C.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013

Hepner Mirta, Karlaftis Vasiliki

Abstract excerpt

Protein C (PC) is a 62-kDa vitamin K-dependent plasma zymogen which, after activation to serine protease, plays an important role in the physiologic regulation of blood coagulation. Given that PC is one of the major naturally occurring inhibitors of coagulation, acquired or hereditary deficiencies of this protein result in excessive thrombin generation. As a vast array of mutations are responsible for hereditary...

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PMID: 23546729
DOI: 10.1007/978-1-62703-339-8_29

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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