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Article

Targeted Therapy of Ewing's Sarcoma

31 Oct 2010

Abstract excerpt

Refractory and/or recurrent Ewing's sarcoma (EWS) remains a clinical challenge because the disease's resistance to therapy makes it difficult to achieve durable results with standard treatments that include chemotherapy, radiation, and surgery. Recently, insulin-like-growth-factor-1-receptor (IGF1R) antibodies have been shown to have a modest single-agent activity in EWS. Patient selection using biomarkers and...

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PMID: 21052545
DOI: 10.1155/2011/686985

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