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Article

Functional effects of a tropomyosin mutation linked to FHC contribute to maladaptation during acidosis.

Journal of molecular and cellular cardiology - 1 Mar 2011

Sheehan Katherine A, Arteaga Grace M, Hinken Aaron C, Dias Fernando A, Ribeiro Cibele, Wieczorek David F, Solaro R John, Wolska Beata M

Abstract excerpt

Familial hypertrophic cardiomyopathy (FHC) is a leading cause of sudden cardiac death among young athletes but the functional effects of the myofilament mutations during FHC-associated ischemia and acidosis, due in part to increased extravascular compressive forces and microvascular dysfunction,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21047515
DOI: 10.1016/j.yjmcc.2010.10.032
PMCID: PMC3035739

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21047515-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Functional effects of a tropomyosin mutation linked to FHC contribute to maladaptation during acidosis.PMID 21047515Read ↗

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