Article
Genetic variants within miR-126 and miR-335 are not associated with breast cancer risk.
Breast cancer research and treatment - 1 Jun 2011
Yang Rongxi, Dick Michelle, Marme Frederik, Schneeweiss Andreas, Langheinz Anne, Hemminki Kari, Sutter Christian, Bugert Peter, Wappenschmidt Barbara, Varon Raymonda, Schott Sarah, Weber Bernhard H F, Niederacher Dieter, Arnold Norbert, Meindl Alfons, Bartram Claus R, Schmutzler Rita K, Müller Heiko, Arndt Volker, Brenner Hermann, Sohn Christof, Burwinkel Barbara
Abstract excerpt
MicroRNAs (miRNAs) are 20-22 nt non-coding RNAs which promote the degradation of target mRNAs or repression of the translation of mRNAs by sequence specific targeting. Many miRNAs are considered as oncogenes or tumor suppressors. MiR-126 and miR-335 play roles in the suppression of breast cancer...
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