Article
[Research Advances of EGFR-TP53 Co-mutation in Advanced Non-small Cell Lung Cancer].
Zhongguo fei ai za zhi = Chinese journal of lung cancer - 20 Mar 2022
Wang Rong, Pan Sisi, Song Xia
Abstract excerpt
With the rapid development and wide application of next generation sequencing (NGS) technology, a series of researches have revealed that concurrent genetic alterations play an important role in the response and resistance of epidermal growth factor receptor (EGFR)-mutant NSCLC to EGFR-tyrosine kinase inhibitor (TKI). Besides, TP53 mutation is the most common co-mutation gene in EGFR-mutant NSCLC, which has been...
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