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Article

Multiple FadD acyl-CoA synthetases contribute to differential fatty acid degradation and virulence in Pseudomonas aeruginosa.

PloS one - 21 Oct 2010

Kang Yun, Zarzycki-Siek Jan, Walton Chad B, Norris Michael H, Hoang Tung T

Abstract excerpt

A close interconnection between nutrient metabolism and virulence factor expression contributes to the pathophysiology of Pseudomonas aeruginosa as a successful pathogen. P. aeruginosa fatty acid (FA) degradation is complicated with multiple acyl-CoA synthetase homologs (FadDs) expressed in vivo in lung tissue during cystic fibrosis infections. The promoters of two genetically linked P. aeruginosa fadD genes...

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Share to Coenzyme A Ligases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21042406
DOI: 10.1371/journal.pone.0013557
PMCID: PMC2958839

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