Article
Pseudomonas aeruginosa aerobic fatty acid desaturase DesB is important for virulence factor production.
Archives of microbiology - 1 Mar 2011
Schweizer Herbert P, Choi Kyoung-Hee
Abstract excerpt
Unsaturated fatty acids (UFAs) play a pivotal role in maintaining a functional cellular membrane in response to changes in environmental factors. Unlike in other gram-negative bacteria, in Pseudomonas aeruginosa, UFA synthesis is governed by 2 pathways: (1) the anaerobic FabAB-mediated pathway and (2) the aerobic inducible DesA/DesB desaturase pathway. Although fatty acids are functional constituents of several...
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