Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Derepression of bkd by the FadR loss dictates elevated production of BCFAs and isoleucine starvation.

Biochimica et biophysica acta. Molecular and cell biology of lipids - 1 Feb 2020

Sun Yijuan, Meng Qiu, Zhang Yongting, Gao Haichun

Abstract excerpt

In many γ-proteobacteria, FadR is recognized as a global transcriptional regulator: in addition to being the most prominent regulator for FA biosynthesis and degradation, the protein also mediates expression of many genes in diverse biological processes. In Shewanella oneidensis, a bacterium renowned for its respiratory versatility, FadR directly controls only a few genes. However, the FadR loss substantially...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)
Share to Amino Acids, Branched-Chain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biosynthetic Pathways

Share to Fatty Acids

Share to Isoleucine

Share to Operon

Share to Regulon

Share to Shewanella

Source

Identifiers

PMID: 31759173
DOI: 10.1016/j.bbalip.2019.158577

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Derepression of bkd by the FadR loss dictates elevated production of BCFAs and isoleucine starvation.PMID 31759173Read ↗

A new glimpse of FadR-DNA crosstalk revealed by deep dissection of the E. coli FadR regulatory protein.Semantic proximity Read ↗

The enigmatic Escherichia coli fadE gene is yafH.Semantic proximity Read ↗

Dissociation between Iron and Heme Biosyntheses Is Largely Accountable for Respiration Defects of Shewanella oneidensis fur Mutants.Semantic proximity Read ↗

Structural Comparison of Acinetobacter baumannii β-ketoacyl-acyl Carrier Protein Reductases in Fatty Acid and Aryl Polyene BiosynthesisSemantic proximity Read ↗

Escherichia coli FadR positively regulates transcription of the fabB fatty acid biosynthetic gene.Semantic proximity Read ↗

Multiple FadD acyl-CoA synthetases contribute to differential fatty acid degradation and virulence in Pseudomonas aeruginosa.Semantic proximity Read ↗

The long-chain fatty acid-CoA ligase FadD1 monitors <i>Pseudomonas aeruginosa</i> quorum sensing as a receptor of cis-2-decenoic acidSemantic proximity Read ↗

A LysR Family Transcriptional Regulator Modulates Burkholderia cenocepacia Biofilm Formation and Protease Production.Semantic proximity Read ↗

Control of proteobacterial central carbon metabolism by the HexR transcriptional regulator: a case study in Shewanella oneidensis.Semantic proximity Read ↗

Haemophilus influenzae Rd lacks a stringently conserved fatty acid biosynthetic enzyme and thermal control of membrane lipid composition.Semantic proximity Read ↗

Comparative whole genome transcriptome and metabolome analyses of five Klebsiella pneumonia strains.Semantic proximity Read ↗

A sensor kinase recognizing the cell-cell signal BDSF (cis-2-dodecenoic acid) regulates virulence in Burkholderia cenocepaciaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.