Article
Improving the prediction of virological response to tipranavir: the development and validation of a tipranavir-weighted mutation score.
Antiviral therapy - 1 Jan 2010
Schapiro Jonathan M, Scherer Joseph, Boucher Charles A, Baxter John D, Tilke Clemens, Perno Carlo F, Maggiolo Franco, Santoro Maria M, Hall David B
Abstract excerpt
BACKGROUND: The purpose of this study was to develop a tipranavir-weighted mutation score that provides guidance to treating physicians on the relative effect of specific protease mutations on tipranavir activity. METHODS: Weights were developed using data from RESIST tipranavir-treated patients...
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