Article
Tipranavir/T20-based salvage regimens highly effective and durable against HIV-1 with evidence for genotypic predictability of response in clinical practice.
International journal of STD & AIDS - 1 Sept 2007
Gupta R K, Loveday Clive, Kalidindi U, Lechelt M, Skinner Celia, Orkin Chloe
Abstract excerpt
Escalating drug resistance in treatment-experienced HIV-1-infected patients has made management increasingly difficult. In clinical trials, tipranavir (TPV) has produced potent and durable responses in such patients, although experience in clinical cohorts is limited. A retrospective clinical case review was undertaken of triple-class experienced HIV-1-infected patients receiving optimized boosted TPV-containing...
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