Article
Genetic analysis of somite formation in laboratory fish models.
Advances in experimental medicine and biology - 1 Jan 2008
Winkler Christoph, Elmasri Harun
Abstract excerpt
The repeated appearance of somites is one of the most fascinating aspects of vertebrate embryogenesis. Recent studies identified complex regulatory circuits that provide the molecular basis for the "clock and wave front" model, postulated almost 30 years ago by Cooke and Zeeman. The highly coordinated process of somite formation involves several networks of molecular cascades including the Delta/Notch, Wnt, FGF...
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