Article
A high omega-3 fatty acid diet has different effects on early and late stage myeloid progenitors.
Lipids - 1 Jan 2011
Varney Melinda E, Buchanan James T, Dementieva Yulia, Hardman W Elaine, Sollars Vincent E
Abstract excerpt
The effects of the polyunsaturated omega-3 (n-3) and omega-6 (n-6) fatty acids (FA) on hematopoiesis are complex in that both FA forms are processed into leukotrienes, eicosanoids, and prostaglandins, which can have independent effects. These FA have antagonistic effects in that n-6 FA prostaglandins tend to be pro-proliferative and pro-inflammatory, while the effects of n-3 FA prostaglandins are the opposite. We...
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