Article
DNA repair deficiency leads to susceptibility to develop arsenic-induced premalignant skin lesions.
International journal of cancer - 15 Jul 2008
Banerjee Mayukh, Sarma Nilendu, Biswas Rupanwita, Roy Jyoeeta, Mukherjee Anita, Giri Ashok K
Abstract excerpt
In West Bengal, India, although more than 6 million people are exposed to arsenic through drinking water, only 15-20% showed arsenic-induced skin lesions, including premalignant hyperkeratosis. This indicates toward some factors that confer susceptibility to arsenic-induced carcinogenicity. In this work, we wanted to explore whether differences in DNA repair capacity could impart arsenic-induced carcinogenicity,...
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