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Article

Various viral compartments in HIV-1-infected mothers contribute to in utero transmission of HIV-1.

AIDS research and human retroviruses - 1 Apr 2011

Kourtis Athena P, Amedee Angela Martin, Bulterys Marc, Danner Susan, Van Dyke Russell, O'Sullivan Mary Jo, Maupin Robert, Jamieson Denise J

Abstract excerpt

Perinatal HIV transmission occurs in utero or intrapartum. The mechanisms and timing of transmission are not clearly understood. To compare the genetic sequences of the V3 envelope region of infant's plasma HIV to that of the mother's plasma, peripheral blood mononuclear cells (PBMC) and vaginal secretions, and correlate with timing of transmission. All 3 infants had a positive HIV PCR in the first days of life,...

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Share to DNA, Viral
Share to env Gene Products, Human Immunodeficiency Virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Infections

Share to Infectious Disease Transmission, Vertical

Share to Leukocytes, Mononuclear

Share to Plasma

Share to Pregnancy Complications, Infectious

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Source

Identifiers

PMID: 21034247
DOI: 10.1089/aid.2010.0160

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