Genotyping HLA-DRB1 and HLA-DQB1 alleles in Japanese patients with normal tension glaucoma.

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Genotyping HLA-DRB1 and HLA-DQB1 alleles in Japanese patients with normal tension glaucoma.

Molecular vision - 15 Sept 2010

Suzuki Misa, Meguro Akira, Ota Masao, Nomura Eiichi, Kato Tetsuo, Nomura Naoko, Kashiwagi Kenji, Mabuchi Fumihiko, Iijima Hiroyuki, Kawase Kazuhide, Yamamoto Tetsuya, Nakamura Makoto, Negi Akira, Sagara Takeshi, Nishida Teruo, Inatani Masaru, Tanihara Hidenobu, Aihara Makoto, Araie Makoto, Fukuchi Takeo, Abe Haruki, Higashide Tomomi, Sugiyama Kazuhisa, Kanamoto Takashi, Kiuchi Yoshiaki, Iwase Aiko, Ohno Shigeaki, Inoko Hidetoshi, Mizuki Nobuhisa

Abstract excerpt

PURPOSE: Normal tension glaucoma (NTG) is a subtype of glaucoma in which intraocular pressure is within the statistically normal range. NTG may be associated with an immune disorder. The aim of this study was to determine whether specific alleles in the human leukocyte antigen (HLA)-DRB1 and HLA-DQB1 genes correlated with NTG in Japanese patients. METHODS: We genotyped the HLA-DRB1 and HLA-DQB1 alleles in 113...

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PMID: 21031025
PMCID: PMC2956698

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