Article
No NRG1 V266L in Chinese patients with schizophrenia.
Psychiatric genetics - 1 Feb 2011
Garcia-Barceló Maria-Mercè, Miao Xiaoping, Tang Clara S, So Hon-Cheong, Tang Waikiu, Leon Thomas Y Y, So Manting, Yip Benjamin, Chen Ronald Y L, Cheung Eric F C, Chen Eric Y H, Li Tao, Tam Paul, Cherny Stacey S, Sham Pak C
Abstract excerpt
NRG1 is one of the best-supported schizophrenia (SZ) susceptibility genes. A NRG1 V266L missense mutation has been found to be associated with SZ in several populations. V266L is not in linkage disequilibrium with any of the SZ-associated NRG1 haplotypes described thus far, and may represent an independent SZ susceptibility locus within NRG1 gene. V266 is a highly conserved residue and its substitution is...
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