Article
Common filaggrin null alleles are not associated with hymenoptera venom allergy in Europeans.
International archives of allergy and immunology - 1 Jan 2011
Aslam A, Lloyd-Lavery A, Warrell D A, Misbah S, Ogg G S
Abstract excerpt
The association of filaggrin mutations with atopic eczema (atopic dermatitis, AD) is well established and it is thought that filaggrin dysfunction impairs the skin's barrier function allowing allergen penetration and subsequent cutaneous sensitisation and inflammation. However, as most forms of b...
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