Article
Transcriptional regulation, occurrence and putative role of the Pht family of Streptococcus pneumoniae.
Microbiology (Reading, England) - 1 Feb 2011
Rioux Stéphane, Neyt Cécile, Di Paolo Emmanuel, Turpin Laurence, Charland Nathalie, Labbé Steve, Mortier Marie-Cécile, Mitchell Tim J, Feron Christiane, Martin Denis, Poolman Jan T
Abstract excerpt
Restricted to the genus Streptococcus, the Pht protein family comprises four members: PhtA, PhtB, PhtD and PhtE. This family has the potential to provide a protein candidate for incorporation in pneumococcal vaccines. Based on sequence analysis and on RT-PCR experiments, we show here that the pht genes are organized in tandem but that their expression, except that of phtD, is monocistronic. PhtD, PhtE, PhtB and...
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