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Article

Elevated interleukin-18 and skewed Th1:Th2 immune response in lupus nephritis.

Rheumatology international - 1 Jan 2012

Liu Xiaoqian, Bao Chunde, Hu Dawei

Abstract excerpt

There is evidence that interleukin-18 plays a role in lupus nephritis (LN). Since interleukin -18 (IL-18) promotes polarization of the immune response toward Th1, we investigated level of IL-18 and assessed the phenotypic distribution of Th1 and Th2 type cells in LN. A predominance of Th1 type (IFN-γ+) cells and significant correlations with serum IL-18 was seen in the patients with LN compared to healthy...

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Source

Identifiers

PMID: 20963419
DOI: 10.1007/s00296-010-1609-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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