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Article

HIV-1 genotypic resistance profile of patients failing antiretroviral therapy in Paraná, Brazil.

The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 1 Jan 2000

Toledo Paula Virginia Michelon, Carvalho Denise Siqueira de, Romagnoli Luiza, Marcinko Gustavo, Cunha Clovis Arns da, Souza Margely Nunes de, Brindeiro Rodrigo, Queiroz-Telles Flávio de

Abstract excerpt

Antiretroviral therapy (ART) has reduced morbidity and mortality related to human immunodeficiency virus (HIV) infection, but in spite of this advance, HIV mutations decrease antiretroviral susceptibility, thus contributing to treatment failure in patients. Genotyping HIV-1 allows the selection of new drugs after initial drug failure. This study evaluated the genotypic profile of HIV-1 isolates from treated...

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PMID: 20963321

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