Article
Antiretroviral resistance in individuals presenting therapeutic failure and subtypes of the human immunodeficiency virus type 1 in the Northeast Region of Brazil.
Memorias do Instituto Oswaldo Cruz - 1 Nov 2007
Cavalcanti Ana Maria Salustiano, Lacerda Heloisa Ramos, Brito Ana Maria de, Pereira Sirleide, Medeiros Daniela, Oliveira Suelene
Abstract excerpt
This study aimed to analyze human immunodeficiency virus (HIV) mutation profiles related to antiretroviral resistance following therapeutic failure, and the distribution of hiv subtypes in the Northeast Region of Brazil. A total of 576 blood samples from AIDS patients presenting therapeutic failure between 2002 and 2004 were analyzed. The genotyping kit viroSeq was used to perform viral amplification in order to...
Topics
- Adult
- Anti-HIV Agents
- Antiretroviral Therapy, Highly Active
- Brazil
- CD4 Lymphocyte Count
- Drug Resistance, Viral
- Female
- Genotype
- HIV Infections
- HIV Protease
- HIV Reverse Transcriptase
- HIV-1
- Humans