Article
Extensive variation in drug-resistance mutational profile of Brazilian patients failing antiretroviral therapy in five large Brazilian cities.
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 1 Jan 2000
Brites Carlos, Pinto-Neto Lauro, Medeiros Melissa, Nunes Estevão, Sprinz Eduardo, Carvalho Mariana
Abstract excerpt
BACKGROUND: Development of drug-resistance mutations is the main cause of failure in antiretroviral therapy. In Brazil, there is scarce information on resistance pattern for patients failing antiretroviral therapy. OBJECTIVES: To define the HIV mutational profile associated with drug resistance in Brazilian patients from 5 large cities, after first, second or further failures to antiretroviral therapy. METHODS:...
Topics
- Adult
- Anti-HIV Agents
- Antiretroviral Therapy, Highly Active
- Drug Resistance, Viral
- Genotype
- HIV Infections
- HIV-1
- Humans
- Mutation
- Reverse Transcriptase Inhibitors
- Viral Load