Article
The association of the Clock 3111 T/C SNP with lipids and lipoproteins including small dense low-density lipoprotein: results from the Mima study.
BMC medical genetics - 21 Oct 2010
Tsuzaki Kokoro, Kotani Kazuhiko, Sano Yoshiko, Fujiwara Shinji, Takahashi Kaoru, Sakane Naoki
Abstract excerpt
BACKGROUND: The clock molecule plays major roles in circadian rhythmicity and regulating lipid and glucose metabolism in peripheral organs. Disruption of the circadian rhythm can lead to cardiometabolic disorders. The existence of small dense low-density lipoprotein (sdLDL) in the circulation, an abnormality of lipid metabolism, in part associated with lifestyle, is also one of risk parameters for cardiometabolic...
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