Article
[Screen and identification of genes involved in multidrug resistance in Pseudomonas aeruginosa].
Wei sheng wu xue bao = Acta microbiologica Sinica - 1 Aug 2008
Zhao Xingyan, Liang Haihua, Shen Lixin, Dong Zhaolin, Duan Kangmin
Abstract excerpt
OBJECTIVE: To identify genes involved in multidrug resistance in Pseudomonas aeruginosa. METHODS: We constructed and screened a transposon mutation library and obtained mutants that exhibited decreased drug resistance. The insertion sites of the transposon were identified by arbitrary PCR and subsequent DNA sequencing. RESULTS: Two mutants which became more susceptible to several antibacterial agents than the...
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