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Article

Design and generation of MLPA probe sets for combined copy number and small-mutation analysis of human genes: EGFR as an example.

TheScientificWorldJournal - 12 Oct 2010

Marcinkowska Malgorzata, Wong Kwok-Kin, Kwiatkowski David J, Kozlowski Piotr

Abstract excerpt

Multiplex ligation-dependent probe amplification (MLPA) is a multiplex copy number analysis method that is routinely used to identify large mutations in many clinical and research labs. One of the most important drawbacks of the standard MLPA setup is a complicated, and therefore expensive, procedure of generating long MLPA probes. This drawback substantially limits the applicability of MLPA to those genomic...

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Identifiers

PMID: 20953551
DOI: 10.1100/tsw.2010.195
PMCID: PMC4004796

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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