Rapid and slow benzbromarone elimination phenotypes in man: benzbromarone and metabolite profiles.

doi:10.1007/BF00316099

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Article

Rapid and slow benzbromarone elimination phenotypes in man: benzbromarone and metabolite profiles.

European journal of clinical pharmacology - 1 Jan 1990

Walter-Sack I, de Vries J X, Ittensohn A, Weber E

Abstract excerpt

Following oral administration of the uricosuric drug benzbromarone two major metabolites appear in the circulation. 1'-hydroxy-benzbromarone (M1), and a second product (M2) of unknown structure. The plasma concentrations of the parent drug and of M1 and M2 have now been compared in two different...

Topics

Adult
Benzbromarone
Biotransformation
Humans
Male
Phenotype

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