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Article

Redox-active antibiotics control gene expression and community behavior in divergent bacteria.

Science (New York, N.Y.) - 29 Aug 2008

Dietrich Lars E P, Teal Tracy K, Price-Whelan Alexa, Newman Dianne K

Abstract excerpt

It is thought that bacteria excrete redox-active pigments as antibiotics to inhibit competitors. In Pseudomonas aeruginosa, the endogenous antibiotic pyocyanin activates SoxR, a transcription factor conserved in Proteo- and Actinobacteria. In Escherichia coli, SoxR regulates the superoxide stress response. Bioinformatic analysis coupled with gene expression studies in P. aeruginosa and Streptomyces coelicolor...

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Identifiers

PMID: 18755976
DOI: 10.1126/science.1160619
PMCID: PMC2745639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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