Article
Apoptotic cell-derived factors induce arginase II expression in murine macrophages by activating ERK5/CREB.
Cellular and molecular life sciences : CMLS - 1 May 2011
Barra Vera, Kuhn Anne-Marie, von Knethen Andreas, Weigert Andreas, Brüne Bernhard
Abstract excerpt
Apoptotic cell (AC)-derived factors alter the physiology of macrophages (MΦs) towards a regulatory phenotype, characterized by reduced nitric oxide (NO) production. Impaired NO formation in response to AC-conditioned medium (CM) was facilitated by arginase II (ARG II) expression, which competes w...
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