Article
Overexpression, amplification, and androgen regulation of TPD52 in prostate cancer.
Cancer research - 1 Jun 2004
Rubin Mark A, Varambally Sooryanarayana, Beroukhim Rameen, Tomlins Scott A, Rhodes Daniel R, Paris Pamela L, Hofer Matthias D, Storz-Schweizer Martina, Kuefer Rainer, Fletcher Jonathan A, Hsi Bae-Li, Byrne Jennifier A, Pienta Kenneth J, Collins Colin, Sellers William R, Chinnaiyan Arul M
Abstract excerpt
Gains in the long arm of chromosome 8 (8q) are believed to be associated with poor outcome and the development of hormone-refractory prostate cancer. Based on a meta-analysis of gene expression microarray data from multiple prostate cancer studies (D. R. Rhodes et al., Cancer Res 2002;62:4427-33), a candidate oncogene, Tumor Protein D52 (TPD52), was identified in the 8q21 amplicon. TPD52 is a coiled-coil...
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