Dicer is required for the formation of white but not brown adipose tissue

Abstract excerpt

Dicer, an enzyme involved in microRNA maturation, is required for proper embryo gastrulation and tissue morphogenesis during mammalian development. Using primary cultures of fibroblasts and pre-adipocytes, we have previously shown that Dicer is essential for early stages of adipogenic cell differentiation. In this study, we have utilized Dicer-conditional mice to explore a role for Dicer and microRNA biogenesis...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Adipokines, Inflammation, and Metabolic Diseases
• Share to Adipose Tissue and Metabolism
• Share to Cardiovascular Disease and Adiposity