Article
Nitrogen starvation reveals the mitotic potential of mutants in the S/MAPK pathways.
Nature communications - 24 Apr 2020
Makarenko Rostyslav, Denis Claire, Francesconi Stefania, Gangloff Serge, Arcangioli Benoît
Abstract excerpt
The genetics of quiescence is an emerging field compared to that of growth, yet both states generate spontaneous mutations and genetic diversity fueling evolution. Reconciling mutation rates in dividing conditions and mutation accumulation as a function of time in non-dividing situations remains a challenge. Nitrogen-starved fission yeast cells reversibly arrest proliferation, are metabolically active and highly...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
