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Article

Genetic causes of frontotemporal degeneration.

Journal of geriatric psychiatry and neurology - 1 Dec 2010

See Tricia M, LaMarre Amanda K, Lee Suzee E, Miller Bruce L

Abstract excerpt

The purpose of this review is to provide a comprehensive update on the genetic causes of frontotemporal lobar degeneration (FTLD). Approximately 40% to 50% of patients diagnosed with FTLD have a family history of a ''related disorder,'' whereas 10% to 40% have an autosomal dominant family history for the disease. At this time, mutations occurring in 2 independent genes located on the same chromosome (MAPT and...

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Identifiers

PMID: 20938042
DOI: 10.1177/0891988710383574

Genes

GRN
MAPT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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