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Article

Regulation of phenotype and secondary metabolic silencing gene clusters in Aspergillus sydowii by velvet transcription factors.

Fungal biology - 1 Aug 2025

Zeng Jie, Cao Yu, Guo Yihan, Xiang Dongyou, Wang Jiale, Xu Qingrui, Lang Xiaoqiang, Xu Hui, Cao Yi

Abstract excerpt

The silencing of biosynthetic gene clusters (BGCs) is a widespread phenomenon in fungal secondary metabolism. Traditional environmental induction strategies often fail to effectively activate these silent BGCs, whereas global transcription factor regulation has emerged as a powerful strategy for their activation. Therefore, this study focuses on Velvet family transcription factors VosA and VelB, investigating...

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PMID: 40707125
DOI: 10.1016/j.funbio.2025.101605

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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