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Article

Reflex testing of resected stage I through III lung adenocarcinomas for EGFR and KRAS mutation: report on initial experience and clinical utility at a single center.

The Journal of thoracic and cardiovascular surgery - 1 Feb 2011

D'Angelo Sandra P, Park Bernard, Azzoli Christopher G, Kris Mark G, Rusch Valerie, Ladanyi Marc, Zakowski Maureen F

Abstract excerpt

OBJECTIVE: The genes KRAS and EGFR have emerged as potential targets for therapy in lung adenocarcinoma; mutations in these genes can be found in almost half of patients. In anticipation of the clinical importance of molecularly defined adenocarcinoma subgroups for the treatment of patients with...

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Identifiers

PMID: 20933246
DOI: 10.1016/j.jtcvs.2010.08.026
PMCID: PMC9136984

Genes

EGFR
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20933246-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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