Article
Mutations of the EGFR and K-ras genes in resected stage I lung adenocarcinoma and their clinical significance.
Surgery today - 1 Mar 2014
Ohba Taro, Toyokawa Gouji, Kometani Takuro, Nosaki Kaname, Hirai Fumihiko, Yamaguchi Masafumi, Hamatake Motoharu, Seto Takashi, Ichinose Yukito, Sugio Kenji
Abstract excerpt
PURPOSE: This study retrospectively assessed the mutations of the epidermal growth factor receptor (EGFR) and K-ras genes and their clinical significance in patients with resected stage I adenocarcinomas. METHODS: A total of 354 patients with resected lung adenocarcinomas were included, and 256 patients with stage I disease were analyzed for the prognostic and predictive value of these mutations. RESULTS:...
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