Article
Reflex testing for epidermal growth factor receptor mutation and anaplastic lymphoma kinase fluorescence in situ hybridization in non-small cell lung cancer.
Archives of pathology & laboratory medicine - 1 May 2011
Mino-Kenudson Mari, Mark Eugene J
Abstract excerpt
CONTEXT: Non-small cell lung cancer (NSCLC) is a poor-prognosis malignancy for which more effective treatments are needed, with accumulating clinical experiences supporting benefits of receptor tyrosine kinase inhibitors for patients with tumors harboring an epidermal growth factor receptor (EGFR) mutation or anaplastic lymphoma kinase ( ALK ) rearrangement. OBJECTIVE: To review completed and ongoing clinical...
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