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Article

No major progranulin genetic variability contribution to disease etiopathogenesis in an ALS Italian cohort.

Neurobiology of aging - 1 Jun 2011

Del Bo Roberto, Corti Stefania, Santoro Domenico, Ghione Isabella, Fenoglio Chiara, Ghezzi Serena, Ranieri Michela, Galimberti Daniela, Mancuso Michelangelo, Siciliano Gabriele, Briani Chiara, Murri Luigi, Scarpini Elio, Schymick Jennifer C, Traynor Bryan J, Bresolin Nereo, Comi Giacomo P

Abstract excerpt

To analyze the contribution of progranulin (PGRN) to the etiopathogenesis of amyotrophic lateral sclerosis (ALS), we performed a PGRN gene screening in 146 Italian patients (12 familial cases) and evaluated the association of two common variants with risk of developing ALS in 239 sporadic cases (...

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Identifiers

PMID: 19632744
DOI: 10.1016/j.neurobiolaging.2009.06.006
PMCID: PMC3511779

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19632744-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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