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DNA methylation of<i>IGF2</i>,<i>GNASAS</i>,<i>INSIGF</i>and<i>LEP</i>and being born small for gestational age

1 Feb 2011

Abstract excerpt

Being born small for gestational age (SGA), a proxy for intrauterine growth restriction (IUGR), and prenatal famine exposure are both associated with a greater risk of metabolic disease. Both associations have been hypothesized to involve epigenetic mechanisms. We investigated whether prenatal growth restriction early in pregnancy was associated with changes in DNA methylation at loci that were previously shown...

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PMID: 20930547
DOI: 10.4161/epi.6.2.13516

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