Article
Oxidative balance in Alzheimer's disease: relationship to APOE, Braak tangle stage, and the concentrations of soluble and insoluble amyloid-β.
Journal of Alzheimer's disease : JAD - 1 Jan 2010
Tayler Hannah, Fraser Thomas, Miners J Scott, Kehoe Patrick G, Love Seth
Abstract excerpt
Oxidative damage is greater in brain tissue from patients with Alzheimer's disease (AD) than age-matched controls. The timing of this damage in relation to other pathogenic processes in AD remains unclear. We have examined the relationship of lipid peroxidation (thiobarbituric acid-reactive substances; TBARS) and antioxidant capacity (Trolox-equivalent) to APOE status, Braak tangle stage, amyloid-β (Aβ) plaque...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
