Article
Candidate genes versus genome-wide associations: which are better for detecting genetic susceptibility to infectious disease?
Proceedings. Biological sciences - 22 Apr 2011
Amos W, Driscoll E, Hoffman J I
Abstract excerpt
Technological developments allow increasing numbers of markers to be deployed in case-control studies searching for genetic factors that influence disease susceptibility. However, with vast numbers of markers, true 'hits' may become lost in a sea of false positives. This problem may be particular...
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