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Article

Systematic removal of outliers to reduce heterogeneity in case-control association studies.

Human heredity - 1 Jan 2010

Shen Yuanyuan, Liu Zhe, Ott Jurg

Abstract excerpt

BACKGROUND/AIMS: In human case-control association studies, population heterogeneity is often present and can lead to increased false-positive results. Various methods have been proposed and are in current use to remedy this situation. METHODS: We assume that heterogeneity is due to a relatively small number of individuals whose allele frequencies differ from those of the remainder of the sample. For this...

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Identifiers

PMID: 20924194
DOI: 10.1159/000320422
PMCID: PMC2975732

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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