Article
Staphylococcus aureus cell growth and division are regulated by an amidase that trims peptides from uncrosslinked peptidoglycan.
Nature microbiology - 1 Feb 2020
Do Truc, Schaefer Kaitlin, Santiago Ace George, Coe Kathryn A, Fernandes Pedro B, Kahne Daniel, Pinho Mariana G, Walker Suzanne
Abstract excerpt
Bacteria are protected by a polymer of peptidoglycan that serves as an exoskeleton1. In Staphylococcus aureus, the peptidoglycan assembly enzymes relocate during the cell cycle from the periphery, where they are active during growth, to the division site where they build the partition between daughter cells2-4. But how peptidoglycan synthesis is regulated throughout the cell cycle is poorly understood5,6. Here,...
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