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Article

Clinical significance of Polycomb gene expression in brain tumors

30 Sept 2010

Abstract excerpt

Polycomb group (PcG) proteins are crucial for neural cancer stem cell (NCSC) self-renewal. However, the relative expression levels of PcG genes in different subtypes of brain tumors, their prognostic role and their effects on cellular pathways have not been investigated. For this purpose, we queried the Oncomine database and found that 4 PcG genes (EZH2, RBBP7, SUZ12, YY1) are specifically expressed in brain...

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PMID: 20920292
DOI: 10.1186/1476-4598-9-265

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