Article
Photochemical modification of lac repressor--III. Mutant I12X86 versus wild-type repressor.
Photochemistry and photobiology - 1 Oct 1990
Spodheim-Maurizot M, Culard F, Grebert P, Maurizot J C, Charlier M
Abstract excerpt
Photodestruction of the two tryptophan (TRP) residues of the core of the wild-type Escherichia coli lac repressor has already been used as a probe in the study of interactions of the repressor with DNA and effectors. The good correlation between phenomena occurring in the core (photodestruction of TRP residues, effectors binding) and at the headpieces (DNA specific and non-specific binding) can be understood in...
Topics
- Escherichia coli
- Mutation
- Photochemistry
- Repressor Proteins
- Ultraviolet Rays