Evolution of dopamine-related systems: biosynthesis, degradation and receptors.

Abstract excerpt

The evolution of enzyme genes at the pathway level has attracted increasing attention in recent years. Most investigations have focused on microorganisms, plants and invertebrates but rarely on vertebrates. The dopamine pathway, which participates in almost every aspect of brain function, is an excellent candidate for study at the pathway level. Herein, we report data on the divergence of six dopamine metabolic...

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